Clinical protocols

Every program at NexusMed begins with a diagnosis. No protocol is applied without prior clinical data. Precision medicine means treatment follows evaluation, not the other way around.

From protocol to treatment room
Every one of these programs happens here, with our own equipment and full clinical traceability.

Certified staff, our in-house GEMA device, and a record of every session parameter.

NexusMed plasmapheresis room in Quito
Longevity · Preventive medicine
Living longer isn't the goal. Living better for longer, with data that anticipates risk, is.
Plasmapheresis · Longevity
Clinical architecture · Regenerative medicine
Stem cells, peptides, or plasmapheresis. Three tools, one clinical logic.
Regenerative · Explained by the team
01 — Therapeutic plasmapheresis
Clinical indication

Immune disorders (Guillain-Barré, myasthenia gravis, lupus, multiple sclerosis, severe asthma) · Liver disease (cirrhosis, hepatitis, liver failure) · Rheumatic disease (rheumatoid arthritis, vasculitis, scleroderma, SLE) · Cardiovascular disease (atherosclerosis, hypertriglyceridemia, cholesterol management) · Infectious/toxic conditions (sepsis, COVID-19 complications, poisoning) · Anti-aging and cellular rejuvenation program

Therapeutic plasma exchange with GEMA technology

Plasmapheresis separates plasma from the cellular components of blood, replacing or filtering the plasma to remove pathological molecules: autoantibodies, immune complexes, pro-inflammatory cytokines, toxins, or excess lipids.

  • Plasma exchange (TPE)
  • Therapeutic plasmapheresis
  • Double filtration
  • Lipid cascade
Protocol

Prior diagnostic evaluation · Baseline immunological and biochemical panel · 3–6 sessions depending on indication · 40–50 min per session (GEMA technology) · Post-protocol follow-up panel

Scientific basis

ASFA category I and II classification for multiple indications. First Spanish-language book on plasmapheresis in Latin America: "Plasmaféresis – Aféresis Terapéutica" (ISBN 978-9978-21-092-5, 2016) — Dr. Zumbana + Prof. Voinov (360+ scientific papers, 25 patents). Procedure performed at 850+ Apheresis Technology centers across 10+ countries.

02 — Cell medicine
Clinical indication

MSC: autoimmune conditions, degenerative joint disease, chronic inflammation. Muse (SAWA): tissue repair, neurological and cardiac recovery, cellular longevity. NK: immune surveillance, complementary oncology support, and chronic infections.

Mesenchymal, Muse (SAWA) and natural killer cell therapy

At NexusMed, cell medicine is not limited to a single cell type. We work with mesenchymal stem cells (MSCs) for their immunomodulatory and regenerative capacity; with Muse cells (SAWA) — the new frontier in cellular innovation, stress-tolerant pluripotent cells with high engraftment and tissue-repair capacity; and with natural killer (NK) cells, central to immune surveillance and complementary oncology support. All are sourced from certified suppliers and administered under an individualized medical protocol.

  • Stem cells
  • Muse cells (SAWA)
  • Natural killer (NK)
  • Mesenchymal (MSC)
NexusMed and Apheresis Technology alliance — innovation and regenerative technology
NexusMed and Apheresis Technology alliance — innovation and regenerative technology
Protocol

Clinical evaluation and biomarkers · Cell type selection (MSC / Muse-SAWA / NK) · Pharmaceutical-grade preparation · Supervised IV or local administration · Follow-up at 30, 60, and 90 days

Scientific basis

MSCs are backed by more than 1,000 clinical trials registered on ClinicalTrials.gov. Muse cells, described by the Dezawa group (Tohoku University), are under clinical investigation for acute myocardial infarction, stroke, and ALS thanks to their ability to home to damaged tissue. NK cells underpin multiple cellular immunotherapy lines. Every NexusMed protocol carries a specific medical indication.

Already available in Ecuador

Mesenchymal, Muse (SAWA) and natural killer cells.

Regenerative medicine of the latest generation with high cell concentration, certified sources, and individualized protocols. Every application requires a medical indication and specialized clinical follow-up.

100–300M
Cells per dose
High
Cell concentration
Clinical
Specialized care
Muse · NK
Muse (SAWA) and natural killer
NexusMed mesenchymal stem cells — regenerative medicine vial
03 — Longevity and preventive medicine
Clinical indication

People aged 35–70 interested in preventive medicine. Ideal for those with a family history of chronic disease, a high-performance lifestyle, or exposure to metabolic, inflammatory, or hormonal risk factors.

Biomarker-driven longevity program

A structured 3–6 month program designed for people without a diagnosed serious condition who want to understand their true biological state, identify early risks, and act before symptoms appear.

  • 80+ biomarkers
  • Biological age
  • Hormonal profile
  • Quarterly review
Protocol

Extended biomarker panel (80+ parameters) · Optional genomic assessment · Body composition analysis · Complete hormonal profile · Personalized intervention protocol · Quarterly review with data comparison

Scientific basis

The precision-medicine paradigm holds that interventions on modifiable biomarkers (inflammation, glucose, lipids, hormones) have a greater impact on healthy life-years than reactive post-diagnosis treatment. (Ref: Lancet 2019, NCD Countdown 2030)

04 — Bioregulator peptides
Clinical indication

Age-related functional decline, recovery after intense physiological stress, support within complementary oncology protocols, mild-to-moderate organ dysfunction without a surgical indication.

Bioregulator peptides and functional restoration

Peptides are short amino-acid sequences with specific biological activity. Bioregulator peptides act on cellular gene expression, with documented effects on tissue regeneration, immune function, and cellular aging processes.

  • BPC-157
  • TB-500
  • Thymosin α1
  • Epitalon
  • CJC-1295 / Ipamorelin
  • GHK-Cu
Technical detail of the GEMA device during a procedure
Clinical instrumentation · detail
Protocol

Peptide selection based on the diagnostic panel · 10–20 day cycles · Subcutaneous or IV administration depending on indication · Response evaluation at 4–6 weeks

Scientific basis

Russian-origin bioregulator peptides (Khavinson peptides) have been studied over more than 30 years of clinical research. At NexusMed they are used in a supervised clinical setting, not as supplements, and require a specific medical indication.

05 — Exosome therapy
Clinical indication

Neuroinflammatory conditions, joint recovery, systemic anti-inflammatory support, longevity protocols with documented markers of accelerated aging.

Stem-cell-derived exosomes

Exosomes are nanoscale extracellular vesicles released by cells that act as biological messengers, carrying proteins, RNA, and lipids between cells. MSC-derived exosomes partially replicate the regenerative and immunomodulatory effects of stem cells without the complexity of direct cell therapy.

Protocol

Mandatory prior evaluation · Preparation under certified sterile conditions · Supervised IV administration · 2–4 session protocol depending on response · Biomarker follow-up

Scientific basis

An emerging field with more than 3,000 PubMed publications in the last 5 years. NexusMed uses exosomes from certified sources under a rigorous medical protocol. They are never applied without a prior diagnostic indication.

06 — Personalized programs
Clinical indication

Complex conditions that do not respond to standard conventional treatment, patients with multiple comorbidities requiring interdisciplinary coordination, cases requiring integration of several of the center's modules.

Individualized multidisciplinary protocols

When a condition requires integrating multiple modalities, the medical team designs a bespoke protocol that can combine apheresis, cell therapy, peptides, IV nutritional support, hormonal optimization, and ongoing biomarker follow-up.

NexusMed multidisciplinary medical team
NexusMed multidisciplinary medical team
Protocol

Extended initial evaluation (2–3 hours) · Complete medical history review · Team-based protocol design · Intervention timeline · Weekly follow-up during the program · Final clinical report

Scientific basis

Precision medicine is built on the premise that every patient has a unique biology. Generic protocols have population-level value; individualized protocols have real clinical value for the specific patient.

Important clinical note

All programs described on this page require prior medical evaluation. No protocol is applied without a documented clinical indication. Results depend on each patient's individual characteristics and cannot be guaranteed in advance. The information presented is educational and does not replace direct medical consultation.

First step

The right program starts with the right evaluation.

Before recommending any protocol, the medical team needs to understand your history, current biomarkers, and goals. The initial consultation is diagnostic, not commercial.

Clinical formulary

What is actually infused: every vial, with an indication.

Peptides, exosomes and clinical-grade intravenous infusions. None are applied generically: selection, dose and number of cycles are defined from the patient's diagnostic panel.

Exosome Secretome
Vial · Cell therapy

Exosome Secretome

MSC-derived extracellular vesicles for regenerative signalling.

GHK-Cu · 50 mg
Vial · Bioregulatory peptide

GHK-Cu · 50 mg

Copper peptide with evidence in tissue repair and dermal matrix.

Glutathione IV
Infusion · Antioxidant

Glutathione IV

Support for oxidative stress and phase II hepatic detoxification.

Vitamin C IV
Infusion · High dose

Vitamin C IV

Dose adjusted by biomarkers, with renal function monitoring.

Myers' Cocktail IV
Infusion · Micronutrients

Myers' Cocktail IV

Magnesium, B complex and vitamin C for fatigue and recovery.

Methylene Blue IV
Infusion · Mitochondrial

Methylene Blue IV

Mitochondrial respiratory chain support in selected protocols.

Use under medical prescription and supervision

Dr. Gerardo Zumbana speaking at an international medical congress
Medical publication

Dr. Zumbana's book: plasmapheresis protocols, regenerative medicine and chronic diagnostics

Available in Spanish, English and Russian for download. ISBN 978-9978-21-092-5.

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